KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKA
All Species:
13.94
Human Site:
S20
Identified Species:
30.67
UniProt:
P23677
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23677
NP_002211.1
461
51009
S20
P
G
G
A
R
P
C
S
P
G
L
E
R
A
P
Chimpanzee
Pan troglodytes
XP_001149577
401
45057
P20
A
P
P
A
P
V
I
P
Q
L
T
V
T
A
E
Rhesus Macaque
Macaca mulatta
XP_001099176
645
70639
E204
A
T
G
Q
C
S
C
E
G
G
G
G
R
A
P
Dog
Lupus familis
XP_544631
632
69191
S191
P
G
G
A
G
P
C
S
P
G
L
E
R
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R071
459
50916
S20
P
R
G
A
G
P
C
S
P
G
L
E
R
A
P
Rat
Rattus norvegicus
P17105
459
50852
S20
P
R
G
A
G
P
C
S
P
G
L
E
R
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990212
452
51079
V23
P
G
P
A
L
S
R
V
P
P
S
L
R
E
W
Frog
Xenopus laevis
NP_001088157
516
58252
S83
D
S
E
Q
R
G
F
S
T
N
D
Q
S
L
H
Zebra Danio
Brachydanio rerio
Q5TZ07
288
31266
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
S184
K
I
F
R
R
K
L
S
G
N
N
M
Q
P
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
70.5
68.6
N.A.
93.2
93.4
N.A.
N.A.
64.6
44.5
21
N.A.
37.6
N.A.
N.A.
42.7
Protein Similarity:
100
86.5
70.8
69.7
N.A.
96
96
N.A.
N.A.
74.6
57.9
32.9
N.A.
46.6
N.A.
N.A.
53.8
P-Site Identity:
100
13.3
40
93.3
N.A.
86.6
86.6
N.A.
N.A.
33.3
13.3
0
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
13.3
40
93.3
N.A.
86.6
86.6
N.A.
N.A.
33.3
20
0
N.A.
20
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
55
0
0
0
0
0
0
0
0
0
55
0
% A
% Cys:
0
0
0
0
10
0
46
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
0
0
0
37
0
10
10
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
28
46
0
28
10
0
0
19
46
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
10
0
0
10
37
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
19
10
0
0
0
0
% N
% Pro:
46
10
19
0
10
37
0
10
46
10
0
0
0
10
46
% P
% Gln:
0
0
0
19
0
0
0
0
10
0
0
10
10
0
0
% Q
% Arg:
0
19
0
10
28
0
10
0
0
0
0
0
55
0
10
% R
% Ser:
0
10
0
0
0
19
0
55
0
0
10
0
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
10
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _